The number of contact lens wearers is ever-growing in China. In order to promote the safety of wearing contact lenses, the Society of Contact Lens Safety Monitoring & Vision Health of Chinese Health Association has conducted extensive discussions on the diagnosis and treatment of adverse reactions of contact lens wear, including the definition, classification, contact lens-related inducements, and therapeutic principles and methods, on the basis of referencing relevant literature and summarizing clinical practice experience, combined with the opinions of experts from relevant professional groups of the Ophthalmology Branch of the Chinese Medical Association. After repeated letter reviews and revisions, this expert consensus is formed for the reference and use of optometry practitioners and clinicians. (Chin J Ophthalmol, 2021, 57: 573-579)